Simulations Plus, Inc. designs and develops software for use in pharmaceutical research and education, and provides contract research services to the pharmaceutical industry. Its software products include ADMET Predictor, a program that enables pharmaceutical researchers to estimate absorption, distribution, metabolism, excretion, and toxicity properties of new chemical entities from their molecular structure; ADMET Modeler, a program that automates the generation of predictive models used in ADMET Predictor; ClassPharmer, a software for screening data analysis, hit-to-lead development, and lead optimization; DDDPlus, a tool that simulates the in vitro disintegration and dissolution of dosage forms in USP Paddle, Basket, and Flow-Through experiments; and GastroPlus, a software program that simulates the dissolution and absorption of a drug in the human gastrointestinal tract. The company also provides contract research and consulting services in the areas oral absorption and pharmacokinetics. In addition, it develops and sells interactive, educational software programs that simulate science experiments conducted in middle school, high school, and junior college science classes. Further, Simulations Plus designs and develops computer software and manufactures augmentative communication devices and computer access products to physically disabled persons, as well as offers Abbreviate!, a productivity software product for the commercial market. It markets augmentative and alternative communication products to speech pathologists, occupational therapists, rehabilitation engineers, special education teachers, disabled persons, and relatives of disabled persons, through a network of employee representatives, independent dealers, and resellers. The company operates in North America, South America, Europe, Asia, and Oceania. It has a collaboration agreement with Enslein Research, Inc. The company was founded in 1996 and is headquartered in Lancaster, California.
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